| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dtox_0482 | Dtox_0549 | Dtox_0482 | Dtox_0549 | PFAM: flavodoxin/nitric oxide synthase; KEGG: sat:SYN_00084 multimeric flavodoxin. | PFAM: Methyltransferase type 11; Methionine biosynthesis MetW protein; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: dvu:DVU0101 UbiE/COQ5 family methlytransferase. | 0.900 |
| Dtox_0482 | menG | Dtox_0482 | Dtox_1999 | PFAM: flavodoxin/nitric oxide synthase; KEGG: sat:SYN_00084 multimeric flavodoxin. | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.900 |
| Dtox_0549 | Dtox_0482 | Dtox_0549 | Dtox_0482 | PFAM: Methyltransferase type 11; Methionine biosynthesis MetW protein; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: dvu:DVU0101 UbiE/COQ5 family methlytransferase. | PFAM: flavodoxin/nitric oxide synthase; KEGG: sat:SYN_00084 multimeric flavodoxin. | 0.900 |
| Dtox_0549 | menG | Dtox_0549 | Dtox_1999 | PFAM: Methyltransferase type 11; Methionine biosynthesis MetW protein; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: dvu:DVU0101 UbiE/COQ5 family methlytransferase. | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.921 |
| Dtox_0962 | menG | Dtox_0962 | Dtox_1999 | TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: dds:Ddes_0751 carboxylyase-related protein; Belongs to the UbiD family. | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.729 |
| Dtox_0962 | mqnC | Dtox_0962 | Dtox_1645 | TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: dds:Ddes_0751 carboxylyase-related protein; Belongs to the UbiD family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.796 |
| Dtox_0962 | mqnE | Dtox_0962 | Dtox_1643 | TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: dds:Ddes_0751 carboxylyase-related protein; Belongs to the UbiD family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.797 |
| Dtox_1248 | Dtox_1641 | Dtox_1248 | Dtox_1641 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: bsu:BSU22740 heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | Geranylgeranyl pyrophosphate synthase-like protein; KEGG: bpt:Bpet4674 putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.932 |
| Dtox_1248 | menG | Dtox_1248 | Dtox_1999 | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: bsu:BSU22740 heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.628 |
| Dtox_1641 | Dtox_1248 | Dtox_1641 | Dtox_1248 | Geranylgeranyl pyrophosphate synthase-like protein; KEGG: bpt:Bpet4674 putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: bsu:BSU22740 heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.932 |
| Dtox_1641 | menG | Dtox_1641 | Dtox_1999 | Geranylgeranyl pyrophosphate synthase-like protein; KEGG: bpt:Bpet4674 putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.523 |
| Dtox_1641 | mqnC | Dtox_1641 | Dtox_1645 | Geranylgeranyl pyrophosphate synthase-like protein; KEGG: bpt:Bpet4674 putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.612 |
| Dtox_1641 | mqnE | Dtox_1641 | Dtox_1643 | Geranylgeranyl pyrophosphate synthase-like protein; KEGG: bpt:Bpet4674 putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.596 |
| Dtox_2000 | menG | Dtox_2000 | Dtox_1999 | KEGG: xfm:Xfasm12_1564 hypothetical protein; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Resolvase domain; regulatory protein MerR; SMART: regulatory protein MerR. | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | 0.445 |
| menG | Dtox_0482 | Dtox_1999 | Dtox_0482 | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | PFAM: flavodoxin/nitric oxide synthase; KEGG: sat:SYN_00084 multimeric flavodoxin. | 0.900 |
| menG | Dtox_0549 | Dtox_1999 | Dtox_0549 | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | PFAM: Methyltransferase type 11; Methionine biosynthesis MetW protein; UbiE/COQ5 methyltransferase; Methyltransferase type 12; KEGG: dvu:DVU0101 UbiE/COQ5 family methlytransferase. | 0.921 |
| menG | Dtox_0962 | Dtox_1999 | Dtox_0962 | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | TIGRFAM: UbiD family decarboxylase; PFAM: Carboxylyase-related protein; KEGG: dds:Ddes_0751 carboxylyase-related protein; Belongs to the UbiD family. | 0.729 |
| menG | Dtox_1248 | Dtox_1999 | Dtox_1248 | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | Trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; KEGG: bsu:BSU22740 heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.628 |
| menG | Dtox_1641 | Dtox_1999 | Dtox_1641 | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | Geranylgeranyl pyrophosphate synthase-like protein; KEGG: bpt:Bpet4674 putative octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.523 |
| menG | Dtox_2000 | Dtox_1999 | Dtox_2000 | 2-heptaprenyl-1,4-naphthoquinonemethyltransferas e; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). | KEGG: xfm:Xfasm12_1564 hypothetical protein; TIGRFAM: DNA binding domain protein, excisionase family; PFAM: Resolvase domain; regulatory protein MerR; SMART: regulatory protein MerR. | 0.445 |