| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dtox_0770 | Dtox_3527 | Dtox_0770 | Dtox_3527 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | 0.463 |
| Dtox_0770 | carA | Dtox_0770 | Dtox_2353 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bsu:BSU15510 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.856 |
| Dtox_0770 | carB | Dtox_0770 | Dtox_2352 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; protein of unknown function DUF201; RimK domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl- phosphate synthetase large chain domain protein; KEGG: bsu:BSU15520 carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.655 |
| Dtox_0770 | pyrB | Dtox_0770 | Dtox_2355 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: sat:SYN_01532 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.947 |
| Dtox_0770 | pyrC | Dtox_0770 | Dtox_2354 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | Dihydroorotase, multifunctional complex type; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.924 |
| Dtox_0770 | pyrE | Dtox_0770 | Dtox_2348 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.864 |
| Dtox_0770 | pyrF | Dtox_0770 | Dtox_2349 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.868 |
| Dtox_0770 | pyrR | Dtox_0770 | Dtox_2356 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | Phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.947 |
| Dtox_3527 | Dtox_0770 | Dtox_3527 | Dtox_0770 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | 0.463 |
| Dtox_3527 | carA | Dtox_3527 | Dtox_2353 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bsu:BSU15510 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | 0.525 |
| Dtox_3527 | pyrB | Dtox_3527 | Dtox_2355 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: sat:SYN_01532 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.630 |
| Dtox_3527 | pyrE | Dtox_3527 | Dtox_2348 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.556 |
| Dtox_3527 | pyrF | Dtox_3527 | Dtox_2349 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.947 |
| Dtox_3527 | pyrH | Dtox_3527 | Dtox_3211 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.963 |
| Dtox_3527 | pyrR | Dtox_3527 | Dtox_2356 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | Phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. | 0.927 |
| Dtox_3527 | surE | Dtox_3527 | Dtox_1365 | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.910 |
| carA | Dtox_0770 | Dtox_2353 | Dtox_0770 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bsu:BSU15510 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: sat:SYN_00733 xanthine permease. | 0.856 |
| carA | Dtox_3527 | Dtox_2353 | Dtox_3527 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bsu:BSU15510 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | TIGRFAM: uracil phosphoribosyltransferase; KEGG: sme:SMc04121 uracil phosphoribosyltransferase; Belongs to the UPRTase family. | 0.525 |
| carA | carB | Dtox_2353 | Dtox_2352 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bsu:BSU15510 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP- binding; protein of unknown function DUF201; RimK domain protein ATP-grasp; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl- phosphate synthetase large chain domain protein; KEGG: bsu:BSU15520 carbamoyl phosphate synthase large subunit; Belongs to the CarB family. | 0.999 |
| carA | pyrB | Dtox_2353 | Dtox_2355 | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: bsu:BSU15510 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. | TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; KEGG: sat:SYN_01532 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |