STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_2359PFAM: (2R)-phospho-3-sulfolactate synthase ComA; KEGG: xau:Xaut_4872 phosphosulfolactate synthase. (273 aa)    
Predicted Functional Partners:
Dtox_2358
PFAM: major facilitator superfamily MFS_1; KEGG: bsu:BSU10980 hypothetical protein.
 
     0.838
Dtox_2357
KEGG: bsu:BSU24440 hypothetical protein.
 
     0.833
Dtox_2360
PFAM: protein of unknown function DUF441; KEGG: abn:AB57_2455 hypothetical protein.
 
     0.798
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
   
    0.620
topB
DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...]
   
    0.620
Dtox_2222
KEGG: nmu:Nmul_A1697 hypothetical protein.
   
    0.620
Dtox_3918
KEGG: psb:Psyr_1929 hypothetical protein.
   
    0.620
Dtox_0169
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: ade:Adeh_2007 4Fe-4S ferredoxin, iron-sulfur binding protein.
   
    0.551
Dtox_2934
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: dat:HRM2_43430 4Fe-4S iron-sulfur binding protein (ferredoxin).
   
    0.551
Dtox_0480
PFAM: Radical SAM domain protein; KEGG: cbg:CbuG_1165 radical SAM superfamily protein.
  
     0.521
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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