STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_2417Sporulation protein YtaF; Probably functions as a manganese efflux pump. (217 aa)    
Predicted Functional Partners:
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.813
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
 
    0.782
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.669
Dtox_2069
PFAM: GerA spore germination protein; KEGG: bha:BH1423 stage V sporulation protein AF.
  
     0.668
Dtox_0603
KEGG: bha:BH3170 hypothetical protein.
  
     0.661
Dtox_3168
TIGRFAM: dipicolinic acid synthetase, A subunit; PFAM: Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: bsu:BSU16730 dipicolinate synthase subunit A.
  
     0.653
Dtox_2270
KEGG: bar:GBAA4621 hypothetical protein.
  
     0.651
Dtox_2697
KEGG: bsu:BSU16880 hypothetical protein.
  
     0.629
Dtox_0222
TIGRFAM: sporulation protein YabP; PFAM: YabP family protein; KEGG: bha:BH0074 hypothetical protein.
  
   
 0.597
Dtox_2050
TIGRFAM: stage II sporulation protein M; PFAM: protein of unknown function DUF95 transmembrane; KEGG: bha:BH1526 stage II sporulation protein M.
  
     0.587
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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