STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_2878KEGG: dps:DP0778 isocitrate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (400 aa)    
Predicted Functional Partners:
Dtox_3767
TIGRFAM: aconitate hydratase; PFAM: aconitate hydratase domain protein; KEGG: afr:AFE_0423 aconitate hydratase.
  
 0.994
Dtox_1989
PFAM: Citrate synthase; KEGG: sfu:Sfum_2105 citrate (Si)-synthase; Belongs to the citrate synthase family.
  
 
 0.965
Dtox_3997
PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: sfu:Sfum_3265 Glu/Leu/Phe/Val dehydrogenase, C terminal; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.960
Dtox_3758
PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: bha:BH1728 glutamate synthase (large subunit).
    
 0.917
folD
Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.892
fhs
PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: fthS; formate-dihydrofolate ligase; K01938 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
 
 
  
 0.889
leuB
3-isopropylmalate dehydrogenase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.843
Dtox_0184
PFAM: fumarate lyase; KEGG: sfu:Sfum_1842 aspartate ammonia-lyase.
     
 0.829
argH
TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: pca:Pcar_2418 argininosuccinate lyase.
     
 0.829
Dtox_1313
PFAM: aminotransferase class I and II; KEGG: gme:Gmet_0732 aspartate aminotransferase.
   
 0.828
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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