STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_2960Multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; KEGG: gme:Gmet_1054 GAF sensor signal transduction histidine kinase. (557 aa)    
Predicted Functional Partners:
Dtox_2959
Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: gur:Gura_2387 two component, sigma-54 specific, fis family transcriptional regulator.
 
 
 0.940
Dtox_1576
KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein.
 
 
0.936
Dtox_1555
KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein.
 
 
0.933
Dtox_3786
GAF sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; GAF domain protein; KEGG: vvu:VV2_0376 signal transduction histidine kinase.
  
 
0.913
Dtox_0616
KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein.
 
0.891
Dtox_3783
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase.
 
0.879
Dtox_2961
PFAM: iron-containing alcohol dehydrogenase; KEGG: gme:Gmet_1053 iron-containing alcohol dehydrogenase.
 
     0.836
Dtox_1918
Multi-sensor signal transduction histidine kinase; KEGG: bsu:BSU13530 two-component sensor histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein.
 
 
 
0.794
Dtox_0066
PFAM: CheW domain protein; response regulator receiver; SMART: CheW domain protein; response regulator receiver; KEGG: bha:BH2262 modulation of CheA activity in response to attractants (chemotaxis protein).
 
 
 0.790
Dtox_1723
KEGG: dat:HRM2_43250 sensory box histidine kinase/response regulator; PFAM: response regulator receiver; Hpt domain protein; SMART: response regulator receiver.
 
 0.782
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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