| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Dtox_0479 | Dtox_1576 | Dtox_0479 | Dtox_1576 | PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: TPR domain-containing protein. | KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein. | 0.421 |
| Dtox_0479 | Dtox_3302 | Dtox_0479 | Dtox_3302 | PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: TPR domain-containing protein. | SMART: Tetratricopeptide domain protein; KEGG: msl:Msil_3125 tetratricopeptide domain protein. | 0.476 |
| Dtox_0479 | rpoA | Dtox_0479 | Dtox_0314 | PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: TPR domain-containing protein. | DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.611 |
| Dtox_0479 | rpoB | Dtox_0479 | Dtox_0278 | PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: TPR domain-containing protein. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.567 |
| Dtox_0479 | rpoZ | Dtox_0479 | Dtox_2317 | PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: TPR domain-containing protein. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.552 |
| Dtox_1322 | Dtox_1555 | Dtox_1322 | Dtox_1555 | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein. | 0.698 |
| Dtox_1322 | Dtox_1576 | Dtox_1322 | Dtox_1576 | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein. | 0.710 |
| Dtox_1322 | Dtox_2180 | Dtox_1322 | Dtox_2180 | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; KEGG: scl:sce7807 hypothetical protein. | 0.667 |
| Dtox_1322 | Dtox_3302 | Dtox_1322 | Dtox_3302 | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | SMART: Tetratricopeptide domain protein; KEGG: msl:Msil_3125 tetratricopeptide domain protein. | 0.465 |
| Dtox_1322 | Dtox_3783 | Dtox_1322 | Dtox_3783 | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase. | 0.588 |
| Dtox_1322 | rpoB | Dtox_1322 | Dtox_0278 | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.425 |
| Dtox_1322 | rpoC | Dtox_1322 | Dtox_0279 | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.431 |
| Dtox_1555 | Dtox_1322 | Dtox_1555 | Dtox_1322 | KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein. | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | 0.698 |
| Dtox_1555 | Dtox_1576 | Dtox_1555 | Dtox_1576 | KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein. | KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein. | 0.995 |
| Dtox_1555 | Dtox_2180 | Dtox_1555 | Dtox_2180 | KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein. | GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; GAF domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; KEGG: scl:sce7807 hypothetical protein. | 0.984 |
| Dtox_1555 | Dtox_3302 | Dtox_1555 | Dtox_3302 | KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein. | SMART: Tetratricopeptide domain protein; KEGG: msl:Msil_3125 tetratricopeptide domain protein. | 0.476 |
| Dtox_1555 | Dtox_3783 | Dtox_1555 | Dtox_3783 | KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein. | Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase. | 0.992 |
| Dtox_1576 | Dtox_0479 | Dtox_1576 | Dtox_0479 | KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein. | PFAM: Tetratricopeptide TPR_2 repeat protein; TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: TPR domain-containing protein. | 0.421 |
| Dtox_1576 | Dtox_1322 | Dtox_1576 | Dtox_1322 | KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein. | 6-deoxyerythronolide-B synthase; PFAM: Acyl transferase; KR domain protein; Beta- ketoacyl synthase; short-chain dehydrogenase/reductase SDR; KEGG: sde:Sde_3725 polyketide synthase modules and related proteins-like. | 0.710 |
| Dtox_1576 | Dtox_1555 | Dtox_1576 | Dtox_1555 | KEGG: sse:Ssed_2865 signal transduction histidine kinase-like protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-3 domain protein; Hpt domain protein; Cache domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain-containing protein; histidine kinase HAMP region domain protein. | KEGG: met:M446_6441 GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; Hpt domain protein; PAS fold- 4 domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; PAS domain-containing protein. | 0.995 |