STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dtox_3774Signal transduction histidine kinase, LytS; KEGG: gme:Gmet_2698 histidine kinase internal region; PFAM: histidine kinase internal region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein. (446 aa)    
Predicted Functional Partners:
Dtox_2345
Two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; KEGG: hypothetical protein.
 
 0.986
Dtox_3773
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA- binding region; SMART: response regulator receiver; KEGG: gur:Gura_2791 LytTR family two component transcriptional regulator.
 
 0.974
Dtox_3783
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase.
 
 
  
 0.912
Dtox_1564
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: ade:Adeh_4321 histidine kinase.
 
 
    0.878
Dtox_3200
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA- binding region; SMART: response regulator receiver; KEGG: glo:Glov_3544 two component transcriptional regulator, LytTR family.
 
 0.874
Dtox_0388
Two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; KEGG: gme:Gmet_2697 LytR/AlgR family transcriptional regulator.
 
 0.872
Dtox_1869
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA- binding region; SMART: response regulator receiver; KEGG: sde:Sde_3900 response regulator receiver domain-containing protein.
 
 
 0.868
Dtox_2766
Two component transcriptional regulator, LytTR family; PFAM: LytTr DNA-binding region; response regulator receiver; SMART: response regulator receiver; KEGG: abu:Abu_0831 two-component response regulator.
 
 
 0.868
Dtox_0399
Two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA- binding region; SMART: response regulator receiver; KEGG: aba:Acid345_3291 transcriptional regulator, LytR/AlgR family.
 
 0.864
nnrE
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
       0.734
Your Current Organism:
Desulfofarcimen acetoxidans
NCBI taxonomy Id: 485916
Other names: D. acetoxidans DSM 771, Desulfofarcimen acetoxidans DSM 771, Desulfotomaculum acetoxidans DSM 771
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