node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Phep_0209 | Phep_2131 | Phep_0209 | Phep_2131 | PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family. | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | 0.405 |
Phep_0209 | dapF | Phep_0209 | Phep_0208 | PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.726 |
Phep_0219 | dapF | Phep_0219 | Phep_0208 | PFAM: NUDIX domain. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.558 |
Phep_2131 | Phep_0209 | Phep_2131 | Phep_0209 | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease, Do/DeqQ family. | 0.405 |
Phep_2131 | Phep_3792 | Phep_2131 | Phep_3792 | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | PFAM: Aminotransferase class I and II. | 0.463 |
Phep_2131 | asd | Phep_2131 | Phep_3654 | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.744 |
Phep_2131 | dapF | Phep_2131 | Phep_0208 | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.727 |
Phep_2131 | murE | Phep_2131 | Phep_3330 | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.418 |
Phep_3605 | dapF | Phep_3605 | Phep_0208 | PFAM: NUDIX domain. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.558 |
Phep_3792 | Phep_2131 | Phep_3792 | Phep_2131 | PFAM: Aminotransferase class I and II. | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | 0.463 |
Phep_3792 | dapB | Phep_3792 | Phep_3529 | PFAM: Aminotransferase class I and II. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.912 |
Phep_3792 | dapF | Phep_3792 | Phep_0208 | PFAM: Aminotransferase class I and II. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.933 |
Phep_3792 | lysA | Phep_3792 | Phep_2332 | PFAM: Aminotransferase class I and II. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.444 |
asd | Phep_2131 | Phep_3654 | Phep_2131 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Glutamate synthase (ferredoxin); PFAM: GXGXG motif; Glutamine amidotransferases class-II; Glutamate synthase central domain; Conserved region in glutamate synthase. | 0.744 |
asd | dapA | Phep_3654 | Phep_3319 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.962 |
asd | dapB | Phep_3654 | Phep_3529 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.777 |
asd | dapF | Phep_3654 | Phep_0208 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.803 |
asd | lysA | Phep_3654 | Phep_2332 | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.509 |
dapA | asd | Phep_3319 | Phep_3654 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.962 |
dapA | dapB | Phep_3319 | Phep_3529 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.983 |