STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Phep_1678PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain. (333 aa)    
Predicted Functional Partners:
Phep_3833
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))., Phosphate acetyltransferase; PFAM: Phosphate acetyl/butaryl transferase; Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; TIGRFAM: phosphate acetyltransferase.
  
 0.947
Phep_4190
PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
 
 0.944
Phep_0543
Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
  
 0.919
Phep_3585
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.915
Phep_4155
Beta-lactamase domain protein; PFAM: Metallo-beta-lactamase superfamily.
  
 0.912
Phep_4178
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
 
 0.905
pdhA
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.904
Phep_3419
Acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, central domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type.
  
 
 0.828
Phep_3420
PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit.
   
 0.820
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
    
 0.819
Your Current Organism:
Pedobacter heparinus
NCBI taxonomy Id: 485917
Other names: P. heparinus DSM 2366, Pedobacter heparinus DSM 2366, Pedobacter heparinus IFO 12017, Pedobacter heparinus LMG 10339, Pedobacter heparinus str. DSM 2366, Pedobacter heparinus strain DSM 2366
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.