Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
outOPrepilin peptidase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (286 aa)    
Predicted Functional Partners:
epsF
Type II secretion system protein F; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.981
PilF
Type IV-A pilus assembly ATPase PilB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.971
pilT_2
Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.959
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
 
  
 0.906
PilQ
Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.875
PilM
Pilus assembly protein PilM; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.862
PilN
Pilus assembly protein PilP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.837
PilO
Pilus assembly protein PilO; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.836
pilT_1
Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.828
pilP
Pilin assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.826
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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