STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smgProtein Smg; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Smg family. (153 aa)    
Predicted Functional Partners:
Smf
DNA-processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.769
ARB03853.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.756
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.754
ARB05446.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.671
ARB03852.1
HAMP domain-containing histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.670
ARB03851.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.652
ARB04977.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.651
ARB03577.1
LPS export ABC transporter periplasmic protein LptC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.627
ARB04492.1
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
     0.610
ARB03585.1
Peptidylprolyl isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.567
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.