STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB03852.1HAMP domain-containing histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (701 aa)    
Predicted Functional Partners:
ARB03851.1
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.979
ARB03853.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.897
ARB03854.1
16S rRNA (cytosine(967)-C(5))-methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
       0.811
smg
Protein Smg; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Smg family.
 
    0.670
Smf
DNA-processing protein DprA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.632
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
       0.621
ompR
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.606
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.597
ARB04598.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.576
ARB03787.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the skp family.
  
     0.529
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.