| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARB04218.1 | ARB04571.1 | B2G52_04405 | B2G52_06425 | D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | 0.934 |
| ARB04218.1 | mrcA | B2G52_04405 | B2G52_04360 | D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.911 |
| ARB04218.1 | mtgA | B2G52_04405 | B2G52_00400 | D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.939 |
| ARB04218.1 | penA | B2G52_04405 | B2G52_00100 | D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.931 |
| ARB04571.1 | ARB04218.1 | B2G52_06425 | B2G52_04405 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
| ARB04571.1 | ftsW | B2G52_06425 | B2G52_00060 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.406 |
| ARB04571.1 | mrcA | B2G52_06425 | B2G52_04360 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.909 |
| ARB04571.1 | mtgA | B2G52_06425 | B2G52_00400 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.910 |
| ARB04571.1 | penA | B2G52_06425 | B2G52_00100 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.920 |
| MtrR | PilQ | B2G52_10985 | B2G52_04335 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| MtrR | gyrA | B2G52_10985 | B2G52_09115 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.775 |
| MtrR | mrcA | B2G52_10985 | B2G52_04360 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.770 |
| MtrR | parC | B2G52_10985 | B2G52_10280 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.775 |
| MtrR | penA | B2G52_10985 | B2G52_00100 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.787 |
| MtrR | rpsJ | B2G52_10985 | B2G52_02005 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.772 |
| PilQ | MtrR | B2G52_04335 | B2G52_10985 | Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| PilQ | gyrA | B2G52_04335 | B2G52_09115 | Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.417 |
| PilQ | mrcA | B2G52_04335 | B2G52_04360 | Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.887 |
| PilQ | penA | B2G52_04335 | B2G52_00100 | Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.782 |
| ftsW | ARB04571.1 | B2G52_00060 | B2G52_06425 | Cell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | 0.406 |
