STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB04250.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)    
Predicted Functional Partners:
ARB05049.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.773
cpxA
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.610
ARB05072.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.505
FumA
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
     
 0.501
ompR
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.477
ARB05499.1
PspA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.475
lpxH
UDP-2,3-diacylglucosamine diphosphatase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
    0.449
macB
Macrolide ABC transporter permease/ATP-binding protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
      
 0.439
ARB04822.1
Hemagglutinin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
B2G52_09430
Hemin transporter; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.415
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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