Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARB04254.1MacA family efflux pump subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (426 aa)    
Predicted Functional Partners:
macB
Macrolide ABC transporter permease/ATP-binding protein MacB; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 0.996
MtrD
Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.948
MtrE
Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.936
ARB04253.1
Prepilin-type cleavage/methylation domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.537
EmrA
Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.492
ARB04762.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S24 family.
  
   
 0.473
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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