STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB04712.1DNA translocase FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FtsK/SpoIIIE/SftA family. (1003 aa)    
Predicted Functional Partners:
ARB04083.1
Chromosome partitioning protein ParB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ParB family.
  
   
 0.765
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
   
 0.703
ARB04711.1
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.634
ARB04647.1
SMI1/KNR4 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.625
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.609
ARB03771.1
Chromosome partitioning protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.572
ComA
DNA internalization-related competence protein ComEC/Rec2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.543
rlpA
Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
      
 0.524
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
   
 
 0.480
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.480
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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