Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ARB04941.1Type IV pilus biogenesis/stability protein PilW; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)    
Predicted Functional Partners:
PilO
Pilus assembly protein PilO; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.803
rlmN
23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
  
    0.796
pilP
Pilin assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.795
PilN
Pilus assembly protein PilP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.794
PilM
Pilus assembly protein PilM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.790
ARB03856.1
Peptidoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.768
PilQ
Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.763
ARB04486.1
Pilus assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.762
B2G52_03145
Competence protein ComEA; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.755
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
  
    0.751
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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