STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB04967.1Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. (494 aa)    
Predicted Functional Partners:
ARB05527.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.771
rppH
RNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
    
 0.720
ARB04966.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.594
ARB05108.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.593
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
     
 0.499
ARB03620.1
Peptidase M23; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.492
msrB
Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
   0.482
B2G52_04545
Sodium:proton antiporter; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S1C family.
 
   
 0.482
ClpA
ATP-dependent Clp protease ATP-binding subunit ClpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family.
     
 0.474
Dgk
Diacylglycerol kinase; Recycling of diacylglycerol produced during the turnover of membrane phospholipid.
      
 0.454
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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