STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARB05207.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (530 aa)    
Predicted Functional Partners:
LpdA
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.995
ompR
DNA-binding response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
ARB05208.1
Sigma-54-dependent Fis family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.982
cpxA
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.907
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
    
 0.852
ARB03856.1
Peptidoglycan-binding protein LysM; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.754
PilN
Pilus assembly protein PilP; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.754
parC
DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
     
 0.747
ARB04486.1
Pilus assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.745
msrB
Trifunctional thioredoxin/methionine sulfoxide reductase A/B protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.722
Your Current Organism:
Neisseria lactamica
NCBI taxonomy Id: 486
Other names: ATCC 23970, CCUG 5853, CIP 72.17, DSM 4691, N. lactamica, NCTC 10617, Neisseria lactamicus
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