| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARB04900.1 | MtrC | B2G52_08405 | B2G52_10980 | Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.703 |
| ARB04900.1 | MtrD | B2G52_08405 | B2G52_10975 | Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.540 |
| ARB04900.1 | MtrE | B2G52_08405 | B2G52_10970 | Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.539 |
| ARB04900.1 | MtrR | B2G52_08405 | B2G52_10985 | Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.713 |
| MtrC | ARB04900.1 | B2G52_10980 | B2G52_08405 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | 0.703 |
| MtrC | MtrD | B2G52_10980 | B2G52_10975 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| MtrC | MtrE | B2G52_10980 | B2G52_10970 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| MtrC | MtrR | B2G52_10980 | B2G52_10985 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| MtrC | PilQ | B2G52_10980 | B2G52_04335 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pilus assembly protein PilQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.411 |
| MtrC | gyrA | B2G52_10980 | B2G52_09115 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.548 |
| MtrC | mrcA | B2G52_10980 | B2G52_04360 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.501 |
| MtrC | penA | B2G52_10980 | B2G52_00100 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | Penicillin-binding protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.728 |
| MtrC | rpsJ | B2G52_10980 | B2G52_02005 | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.415 |
| MtrD | ARB04900.1 | B2G52_10975 | B2G52_08405 | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. | 0.540 |
| MtrD | MtrC | B2G52_10975 | B2G52_10980 | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Efflux transporter periplasmic adaptor subunit; MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| MtrD | MtrE | B2G52_10975 | B2G52_10970 | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
| MtrD | MtrR | B2G52_10975 | B2G52_10985 | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.884 |
| MtrD | gyrA | B2G52_10975 | B2G52_09115 | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.582 |
| MtrD | mrcA | B2G52_10975 | B2G52_04360 | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). | 0.508 |
| MtrD | parC | B2G52_10975 | B2G52_10280 | Multidrug efflux RND transporter permease subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.531 |
