STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAFB16201RNA polymerase II-associated protein. (504 aa)    
Predicted Functional Partners:
PAFA16201
RNA polymerase II-associated protein.
   
 0.999
PAFC16201
RNA polymerase II-associated protein.
   
 0.999
PAFE16201
RNA polymerase II-associated protein.
   
 0.999
GTC16201
Predicted protein.
   
 0.999
B0D4C2_LACBS
Predicted protein.
   
 0.999
B0D590_LACBS
Predicted protein.
   
 0.999
B0DK51_LACBS
Predicted protein.
    
 0.999
GTG16201
Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
    
 0.996
B0CRL0_LACBS
Predicted protein.
   
 0.994
GTB16201
Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family.
   
 0.994
Your Current Organism:
Laccaria bicolor
NCBI taxonomy Id: 486041
Other names: L. bicolor S238N-H82, Laccaria bicolor S238N-H82
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.