B0CYA8_LACBS protein (Laccaria bicolor) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B0CYA8_LACBS

Carbohydrate esterase family 4 protein. (430 aa)

Predicted Functional Partners:

B0CP68_LACBS

0.901

B0CXP1_LACBS

0.900

B0D0H4_LACBS

0.900

B0D121_LACBS

0.900

B0D461_LACBS

0.900

B0DQH5_LACBS

0.900

B0DTW8_LACBS

0.900

B0DTW9_LACBS

0.900

B0DJT6_LACBS

0.696

B0DQI5_LACBS

0.514

Your Current Organism:

Laccaria bicolor

NCBI taxonomy Id: 486041
Other names: L. bicolor S238N-H82, Laccaria bicolor S238N-H82

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0CP68_LACBS	B0CYA8_LACBS	B0CP68	B0CYA8	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	Carbohydrate esterase family 4 protein.	0.901
B0CXP1_LACBS	B0CYA8_LACBS	B0CXP1	B0CYA8	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	Carbohydrate esterase family 4 protein.	0.900
B0CYA8_LACBS	B0CP68_LACBS	B0CYA8	B0CP68	Carbohydrate esterase family 4 protein.	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	0.901
B0CYA8_LACBS	B0CXP1_LACBS	B0CYA8	B0CXP1	Carbohydrate esterase family 4 protein.	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	0.900
B0CYA8_LACBS	B0D0H4_LACBS	B0CYA8	B0D0H4	Carbohydrate esterase family 4 protein.	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	0.900
B0CYA8_LACBS	B0D121_LACBS	B0CYA8	B0D121	Carbohydrate esterase family 4 protein.	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	0.900
B0CYA8_LACBS	B0D461_LACBS	B0CYA8	B0D461	Carbohydrate esterase family 4 protein.	Glycoside hydrolase family 18 protein.	0.900
B0CYA8_LACBS	B0DJT6_LACBS	B0CYA8	B0DJT6	Carbohydrate esterase family 4 protein.	Predicted protein.	0.696
B0CYA8_LACBS	B0DQH5_LACBS	B0CYA8	B0DQH5	Carbohydrate esterase family 4 protein.	Chitinase; Belongs to the glycosyl hydrolase 18 family.	0.900
B0CYA8_LACBS	B0DQI5_LACBS	B0CYA8	B0DQI5	Carbohydrate esterase family 4 protein.	Carbohydrate esterase family 4 protein.	0.514
B0CYA8_LACBS	B0DTW8_LACBS	B0CYA8	B0DTW8	Carbohydrate esterase family 4 protein.	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	0.900
B0CYA8_LACBS	B0DTW9_LACBS	B0CYA8	B0DTW9	Carbohydrate esterase family 4 protein.	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	0.900
B0D0H4_LACBS	B0CYA8_LACBS	B0D0H4	B0CYA8	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	Carbohydrate esterase family 4 protein.	0.900
B0D121_LACBS	B0CYA8_LACBS	B0D121	B0CYA8	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	Carbohydrate esterase family 4 protein.	0.900
B0D461_LACBS	B0CYA8_LACBS	B0D461	B0CYA8	Glycoside hydrolase family 18 protein.	Carbohydrate esterase family 4 protein.	0.900
B0DJT6_LACBS	B0CYA8_LACBS	B0DJT6	B0CYA8	Predicted protein.	Carbohydrate esterase family 4 protein.	0.696
B0DQH5_LACBS	B0CYA8_LACBS	B0DQH5	B0CYA8	Chitinase; Belongs to the glycosyl hydrolase 18 family.	Carbohydrate esterase family 4 protein.	0.900
B0DQI5_LACBS	B0CYA8_LACBS	B0DQI5	B0CYA8	Carbohydrate esterase family 4 protein.	Carbohydrate esterase family 4 protein.	0.514
B0DTW8_LACBS	B0CYA8_LACBS	B0DTW8	B0CYA8	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	Carbohydrate esterase family 4 protein.	0.900
B0DTW9_LACBS	B0CYA8_LACBS	B0DTW9	B0CYA8	Glycoside hydrolase family 18 protein; Belongs to the glycosyl hydrolase 18 family.	Carbohydrate esterase family 4 protein.	0.900

Network Stats

number of nodes:

6

number of edges:

9

average node degree:

3

avg. local clustering coefficient:

0.8

expected number of edges:

8

PPI enrichment p-value:

0.412

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000387

Spliceosomal snRNP assembly

4 of 30

2.45

2.86

3.49e-06

GO:0040031

snRNA modification

3 of 8

2.9

2.63

1.54e-05

GO:0008380

RNA splicing

6 of 351

1.55

1.92

9.26e-06

GO:0000398

mRNA splicing, via spliceosome

5 of 229

1.66

1.86

4.08e-05

GO:0016071

mRNA metabolic process

7 of 575

1.41

1.78

3.85e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0017069

snRNA binding

7 of 39

2.58

6.59

6.85e-14

GO:0017070

U6 snRNA binding

4 of 8

3.02

4.21

1.86e-08

GO:0003723

RNA binding

9 of 1208

1.19

1.57

1.37e-07

GO:0097322

7SK snRNA binding

2 of 5

2.92

1.46

0.0023

GO:1901363

Heterocyclic compound binding

10 of 6430

0.51

0.37

0.0105

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030532

Small nuclear ribonucleoprotein complex

5 of 59

2.25

3.5

8.06e-08

GO:0046540

U4/U6 x U5 tri-snRNP complex

4 of 32

2.42

3.19

6.88e-07

GO:0015030

Cajal body

4 of 36

2.37

3.17

6.88e-07

GO:0071005

U2-type precatalytic spliceosome

4 of 48

2.24

2.95

1.35e-06

GO:1990904

Ribonucleoprotein complex

7 of 598

1.39

1.89

6.88e-07

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:19743

Regulation of protein localization to Cajal body, and U6 snRNA 3-end binding

4 of 6

3.15

4.14

2.82e-08

CL:18977

Small nuclear ribonucleoprotein complex, and snRNA binding

5 of 66

2.2

3.24

2.60e-07

CL:19047

Spliceosomal tri-snRNP complex assembly, and U4/U6 x U5 tri-snRNP complex

3 of 10

2.8

2.65

1.34e-05

CL:18979

Spliceosomal snRNP complex, and snRNA binding

4 of 60

2.15

2.46

1.20e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03040

Spliceosome

4 of 266

1.5

1.26

0.0011

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72203

Processing of Capped Intron-Containing Pre-mRNA

5 of 391

1.43

1.31

0.00051

MAP-8953854

Metabolism of RNA

7 of 946

1.19

1.21

9.46e-05

MAP-72163

mRNA Splicing - Major Pathway

4 of 272

1.49

1.09

0.0034

MAP-72172

mRNA Splicing

4 of 296

1.45

1.06

0.0036

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990904

Ribonucleoprotein complex

7 of 447

1.52

2.16

5.13e-07

GOCC:0005634

Nucleus

8 of 3501

0.68

0.43

0.0232

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (28%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About