close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
actPCation acetate symporter; Member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (575 aa)    
Predicted Functional Partners:
AOD13597.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.996
acs
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.849
BER92_01095
NdvB protein; Internal stop; incomplete; partial on complete genome; missing start and stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.642
AOD13596.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.582
AOD14492.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.419
AOD15032.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.419
xthA2
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.401
AOD13600.1
Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.401
Your Current Organism:
Xanthomonas fragariae
NCBI taxonomy Id: 48664
Other names: ATCC 33239, CCUG 23372, CFBP 2157, DSM 3587, ICMP 5715, LMG 708, LMG:708, VKM B-2165, X. fragariae
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.