| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOD13615.1 | birA | BER92_01270 | BER92_01260 | Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.829 |
| AOD13615.1 | coaX | BER92_01270 | BER92_01265 | Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.815 |
| AOD13828.1 | AOD14061.1 | BER92_02700 | BER92_04150 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| AOD13828.1 | birA | BER92_02700 | BER92_01260 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.823 |
| AOD14061.1 | AOD13828.1 | BER92_04150 | BER92_02700 | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| AOD14061.1 | AOD14175.1 | BER92_04150 | BER92_04825 | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| AOD14061.1 | birA | BER92_04150 | BER92_01260 | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.920 |
| AOD14061.1 | tadA | BER92_04150 | BER92_11735 | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.558 |
| AOD14175.1 | AOD14061.1 | BER92_04825 | BER92_04150 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.409 |
| AOD14175.1 | birA | BER92_04825 | BER92_01260 | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.823 |
| AOD16016.1 | accC | BER92_16640 | BER92_16270 | 3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.586 |
| AOD16016.1 | birA | BER92_16640 | BER92_01260 | 3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.934 |
| accC | AOD16016.1 | BER92_16270 | BER92_16640 | Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.586 |
| accC | birA | BER92_16270 | BER92_01260 | Hypothetical protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.805 |
| bioB | birA | BER92_17655 | BER92_01260 | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.970 |
| birA | AOD13615.1 | BER92_01260 | BER92_01270 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Sporulation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.829 |
| birA | AOD13828.1 | BER92_01260 | BER92_02700 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
| birA | AOD14061.1 | BER92_01260 | BER92_04150 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA N6-adenosine(37)-N6-threonylcarbamoyltransferase complex dimerization subunit TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
| birA | AOD14175.1 | BER92_01260 | BER92_04825 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA-specific adenosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.823 |
| birA | AOD16016.1 | BER92_01260 | BER92_16640 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 3-methylcrotonyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
