| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOD14136.1 | AOD14138.1 | BER92_04590 | BER92_04600 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.486 |
| AOD14136.1 | bioB | BER92_04590 | BER92_17655 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.432 |
| AOD14136.1 | birA | BER92_04590 | BER92_01260 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.463 |
| AOD14136.1 | dusB | BER92_04590 | BER92_04595 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.708 |
| AOD14136.1 | entF | BER92_04590 | BER92_18470 | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.414 |
| AOD14138.1 | AOD14136.1 | BER92_04600 | BER92_04590 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.486 |
| AOD14138.1 | dusB | BER92_04600 | BER92_04595 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.542 |
| bioB | AOD14136.1 | BER92_17655 | BER92_04590 | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.432 |
| bioB | birA | BER92_17655 | BER92_01260 | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.966 |
| birA | AOD14136.1 | BER92_01260 | BER92_04590 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.463 |
| birA | bioB | BER92_01260 | BER92_17655 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Biotin synthase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.966 |
| birA | entF | BER92_01260 | BER92_18470 | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.486 |
| dusB | AOD14136.1 | BER92_04595 | BER92_04590 | tRNA dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.708 |
| dusB | AOD14138.1 | BER92_04595 | BER92_04600 | tRNA dihydrouridine synthase DusB; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.542 |
| entF | AOD14136.1 | BER92_18470 | BER92_04590 | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.414 |
| entF | birA | BER92_18470 | BER92_01260 | Non-ribosomal peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. | biotin--[acetyl-CoA-carboxylase] ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.486 |