Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
egtDDimethylhistidine N-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)    
Predicted Functional Partners:
AOD16328.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.997
hutH
Histidine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
     
  0.900
AOD16745.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.741
AOD16329.1
Selenocysteine lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.731
AOD16330.1
Amino acid ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.558
nnrD-2
Bifunctional ADP-dependent (S)-NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-spec [...]
      
 0.548
gsh1
Two-component sensor histidine kinase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
  
  
 0.505
AOD16443.1
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.497
AOD15555.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.497
Your Current Organism:
Xanthomonas fragariae
NCBI taxonomy Id: 48664
Other names: ATCC 33239, CCUG 23372, CFBP 2157, DSM 3587, ICMP 5715, LMG 708, LMG:708, VKM B-2165, X. fragariae
Server load: low (10%) [HD]