Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC103155213Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily. (350 aa)    
Predicted Functional Partners:
LOC103154558
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.992
ENSPFOP00000003961
Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family.
   
 0.992
FUNDC1
FUN14 domain containing 1.
   
 0.963
fundc1
Uncharacterized protein.
   
 0.963
ENSPFOP00000004707
Zgc:86598; Belongs to the protein kinase superfamily.
  
  
 
0.950
LOC103152715
Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily.
  
  
 
0.950
ctnnb1
Catenin (cadherin-associated protein), beta 1.
    
 0.920
LOC103135024
Uncharacterized protein.
    
  0.910
CSNK2A2
Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily.
  
  
 
0.900
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.897
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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