Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IPO8Importin 8. (1019 aa)    
Predicted Functional Partners:
ENSPFOP00000006851
Karyopherin (importin) beta 3.
   
 
 0.936
ran
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
   
 0.917
ENSPFOP00000017429
Adhesion G protein-coupled receptor D1; Belongs to the G-protein coupled receptor 2 family.
   
 0.917
ipo4
Importin 4.
   
 
 0.904
kpnb1
Karyopherin (importin) beta 1.
   
 
 0.898
ENSPFOP00000018153
Glutamyl-prolyl-tRNA synthetase.
   
 0.870
ipo9
Importin 9.
   
 
 0.850
exosc10
Exosome component 10.
   
 0.845
ttc37
Tetratricopeptide repeat domain 37.
   
 0.835
ENSPFOP00000018045
WD repeat domain 3.
   
 0.834
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (12%) [HD]