Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dclre1bDNA cross-link repair 1B. (569 aa)    
Predicted Functional Partners:
terf2
HTH myb-type domain-containing protein.
    
 
 0.992
ENSPFOP00000013181
BRCT domain-containing protein.
    
 
 0.988
ENSPFOP00000009033
TERF1 (TRF1)-interacting nuclear factor 2.
   
 
 0.944
pot1
Telo_bind domain-containing protein.
   
 
 0.927
xrcc5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
    
 0.905
fan1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
    
 0.869
ENSPFOP00000002114
Helicase C-terminal domain-containing protein.
   
 0.863
lig4
DNA ligase.
   
 0.861
mus81
MUS81 structure-specific endonuclease subunit.
  
 0.860
xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
    
 0.855
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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