Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103152451Uncharacterized protein. (465 aa)    
Predicted Functional Partners:
nf1
Neurofibromin 1b.
    
 0.890
sqstm1
Sequestosome 1.
    
   0.749
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.704
hras
HRas proto-oncogene, GTPase a.
   
 0.691
LOC103145420
Zgc:55558.
   
 0.691
KRAS
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.691
CSDE1
Cold shock domain containing E1, RNA-binding.
   
 0.691
ofd1
OFD1 centriole and centriolar satellite protein.
    
 
 0.669
RALB
RAS like proto-oncogene B.
   
 0.618
LOC103150928
Uncharacterized protein.
   
 0.618
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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