Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001117Ubiquitin-conjugating enzyme E2Z. (402 aa)    
Predicted Functional Partners:
uba1
Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family.
  
 0.944
LOC103137255
Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
  
 0.944
uba6
Ubiquitin like modifier activating enzyme 6.
  
 0.944
rps27a
Ribosomal protein S27a.
    
 0.931
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
    
  0.910
ubb
Ubiquitin B.
    
 0.880
LOC103147165
Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
    
 0.879
trip12
Thyroid hormone receptor interactor 12.
   
 0.871
LOC103139106
Ubiquitin-conjugating enzyme E2 variant 1.
    
 0.859
ENSPFOP00000005486
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 0.853
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.