Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (805 aa)    
Predicted Functional Partners:
gucy1b1
Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
0.998
ENSPFOP00000005129
Si:dkey-121j17.5; Belongs to the protein kinase superfamily.
  
 0.927
prkg2
cGMP-dependent protein kinase.
  
 0.927
ENSPFOP00000015658
cGMP-dependent protein kinase.
  
 0.927
pde9a
Phosphodiesterase 9A like; Belongs to the cyclic nucleotide phosphodiesterase family.
   
 0.906
gucy1a1
Guanylate cyclase 1 soluble subunit alpha 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
  
 
0.902
nudt2
Nudix (nucleoside diphosphate linked moiety X)-type motif 2.
    
  0.900
ENSPFOP00000000508
Phosphodiesterase.
   
 0.867
ENSPFOP00000016853
PDEase domain-containing protein; Belongs to the cyclic nucleotide phosphodiesterase family.
   
 0.823
ENSPFOP00000003443
Phosphodiesterase.
   
 0.804
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (24%) [HD]