close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GUCY1A2Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (805 aa)    
Predicted Functional Partners:
gucy1b1
Guanylate cyclase 1 soluble subunit beta 1; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
  
0.997
ENSPFOP00000005129
Si:dkey-121j17.5; Belongs to the protein kinase superfamily.
   
 0.968
prkg2
cGMP-dependent protein kinase.
   
 0.968
nudt2
Nudix (nucleoside diphosphate linked moiety X)-type motif 2.
    
 0.952
LOC103130154
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.944
LOC103138114
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.944
pde9a
Phosphodiesterase 9A like; Belongs to the cyclic nucleotide phosphodiesterase family.
   
 0.935
entpd1
Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family.
   
 
  0.933
ENSPFOP00000007334
cGMP-dependent protein kinase.
   
 0.929
ENSPFOP00000015658
cGMP-dependent protein kinase.
   
 0.929
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.