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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (526 aa)    
Predicted Functional Partners:
mras
Muscle RAS oncogene homolog.
   
 0.924
hras
HRas proto-oncogene, GTPase a.
   
 0.924
LOC103145420
Zgc:55558.
   
 0.924
KRAS
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.923
ENSPFOP00000008861
RAS related.
   
 0.921
rras2
RAS related 2.
   
 0.915
araf
A-Raf proto-oncogene, serine/threonine kinase.
    
0.909
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
0.909
ENSPFOP00000000274
Myosin, light chain kinase a.
   
 
 
0.893
RDX
Radixin.
   
 
  0.893
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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