Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001194Uncharacterized protein. (382 aa)    
Predicted Functional Partners:
ENSPFOP00000014652
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
    
 0.913
LOC103151735
Scavenger receptor class B, member 1; Belongs to the CD36 family.
   
 
 0.810
ENSPFOP00000013278
Uncharacterized protein.
   
 0.723
ENSPFOP00000014181
Uncharacterized protein.
   
 0.723
ENSPFOP00000011150
Solute carrier family 3 member 1.
   
  
 0.684
ENSPFOP00000017013
Angiotensin-converting enzyme.
   
 
 0.667
cltrn
Si:dkey-194e6.1.
   
 
 0.667
ENSPFOP00000000899
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
    
 0.643
cask
Uncharacterized protein; Belongs to the MAGUK family.
    
 0.643
ift88
Intraflagellar transport 88 homolog.
    
 0.604
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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