Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
prune1Prune exopolyphosphatase. (414 aa)    
Predicted Functional Partners:
hddc3
HD domain containing 3.
     
 0.917
LOC103143437
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 
 0.878
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
    
 
 0.878
LOC103136805
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 
 0.878
gmppb
GDP-mannose pyrophosphorylase B.
    
   0.775
ENSPFOP00000003915
UTP20 small subunit processome component.
      
 0.710
ppp1r11
Protein phosphatase 1, regulatory (inhibitor) subunit 11.
      
 0.689
ENSPFOP00000017529
MMS19 homolog, cytosolic iron-sulfur assembly component.
      
 0.678
LOC103149331
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
      
 0.661
ENSPFOP00000008471
Zgc:174895.
    
 0.647
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.