Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSPFOP00000001207Glutamate receptor, ionotropic, AMPA 1a. (726 aa)    
Predicted Functional Partners:
LOC103146616
Uncharacterized protein.
   
 0.899
GRIA2
Glutamate receptor, ionotropic, AMPA 2b.
   
 0.899
ENSPFOP00000019089
Cornichon family AMPA receptor auxiliary protein 2.
    
 0.836
LOC103144737
Cornichon family AMPA receptor auxiliary protein 1.
    
 0.829
pick1
Protein interacting with prkca 1.
    
 0.817
cnih4
Cornichon family AMPA receptor auxiliary protein 4.
    
 0.783
ENSPFOP00000012744
Glutamate receptor interacting protein 1.
   
 0.764
ENSPFOP00000008934
Glutamate receptor interacting protein 2b.
    
 0.761
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 0.753
LOC103141690
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 0.753
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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