Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001212Keratin 5; Belongs to the intermediate filament family. (533 aa)    
Predicted Functional Partners:
LOC103143006
Uncharacterized protein.
     
  0.800
ENSPFOP00000029272
Uncharacterized protein; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
     
  0.800
LOC103139106
Ubiquitin-conjugating enzyme E2 variant 1.
   
 0.786
bag3
BCL2 associated athanogene 3.
    
 0.783
ube2w
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.616
ENSPFOP00000005486
E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily.
    
 
 0.602
bag2
BCL2 associated athanogene 2.
    
 
 0.591
LOC103153586
Runt-related transcription factor.
    
  0.573
LOC103130586
Runt-related transcription factor.
    
  0.573
ENSPFOP00000013771
Runt domain-containing protein.
    
  0.573
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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