Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gtf2a1General transcription factor IIA, 1. (393 aa)    
Predicted Functional Partners:
gtf2a2
Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.
    
 0.999
ENSPFOP00000010827
TBP-like 1.
   
 0.994
gtf2e2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
    
 0.991
gtf2b
General transcription factor IIB.
   
 0.978
ENSPFOP00000008518
General transcription factor IIE, polypeptide 1, alpha.
    
 0.976
taf12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
   
 0.975
ENSPFOP00000014830
TATA box binding protein.
   
 0.975
ENSPFOP00000001063
Uncharacterized protein.
   
 0.974
ercc3
Excision repair cross-complementation group 3.
    
 0.969
ENSPFOP00000002806
TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.
   
 0.959
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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