Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
fgf8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)    
Predicted Functional Partners:
ENSPFOP00000019287
Fibroblast growth factor receptor.
    
 0.987
LOC103148401
Fibroblast growth factor receptor.
    
 0.985
ENSPFOP00000003140
Fibroblast growth factor receptor.
    
 0.975
LOC103131912
Fibroblast growth factor receptor 4.
    
 0.975
LOC103152302
Fibroblast growth factor receptor.
    
 0.964
ENSPFOP00000008302
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 
 0.957
ENSPFOP00000029385
Ret proto-oncogene receptor tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.930
ENSPFOP00000006794
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
  0.909
LOC103140457
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.891
ENSPFOP00000017767
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
    
 0.877
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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