STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001337Uncharacterized protein. (69 aa)    
Predicted Functional Partners:
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
   
 0.964
ENSPFOP00000007356
Intersectin 2a.
    
 0.963
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 0.963
ENSPFOP00000011660
Intersectin 2b.
    
 0.963
ENSPFOP00000008789
Adaptor related protein complex 2 subunit alpha 1.
   
 0.962
ENSPFOP00000011705
AP-1 complex subunit gamma.
   
 0.949
gak
Cyclin G associated kinase.
   
 0.936
ap1g1
AP-1 complex subunit gamma.
   
 0.931
itsn1
Intersectin 1 (SH3 domain protein).
    
 0.925
ldlrap1
Low density lipoprotein receptor adaptor protein 1b.
    
 0.921
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.