Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001349Si:ch211-193k19.1. (918 aa)    
Predicted Functional Partners:
ENSPFOP00000012895
Zgc:153240.
      
 0.666
ap2m1
AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]
     
 0.644
dnaaf4
Dynein axonemal assembly factor 4.
      
 0.639
ENSPFOP00000011705
AP-1 complex subunit gamma.
    
  0.599
ubqln4
Ubiquilin 4.
    
  0.598
acot13
Acyl-CoA thioesterase 13.
      
 0.568
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
     
  0.564
fam91a1
Family with sequence similarity 91 member A1.
      
 0.564
ENSPFOP00000013752
Tyrosyl-DNA phosphodiesterase 2b.
      
 0.559
SYT8
Uncharacterized protein.
    
  0.537
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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