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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sall4Spalt-like transcription factor 4. (1081 aa)    
Predicted Functional Partners:
LOC103147705
POU domain protein.
   
 0.960
LOC103129685
WD_REPEATS_REGION domain-containing protein.
   
 0.900
ENSPFOP00000008113
Retinoblastoma binding protein 4.
   
 0.900
crbn
Cereblon.
    
 
 0.813
wdr73
WD repeat domain 73.
    
 0.733
LOC103149827
Methyl-CpG binding domain protein 3a.
   
 0.712
mbd2
Methyl-CpG binding domain protein 2.
   
 0.712
HDAC2
Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.705
NR0B1
Nuclear receptor subfamily 0 group B member 1.
    
 0.689
bsx
Brain-specific homeobox.
   
 0.683
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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