Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSPFOP00000001361Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (372 aa)    
Predicted Functional Partners:
gng2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.876
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.876
gnb1
Guanine nucleotide binding protein (G protein), beta polypeptide 1a.
    
  0.870
LOC103145639
Guanine nucleotide binding protein (G protein), beta polypeptide 2.
    
  0.870
GNB4
Guanine nucleotide binding protein (G protein), beta polypeptide 4b.
    
  0.870
LOC103137054
Guanine nucleotide binding protein (G protein), beta polypeptide 1b.
    
  0.870
gnao1
Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b.
    
 0.839
GNAI2
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a.
    
 0.839
LOC103151060
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3.
    
 0.839
LOC103137272
Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b.
    
 0.839
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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