Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSPFOP00000001367Leucine-rich repeat containing G protein-coupled receptor 4. (977 aa)    
Predicted Functional Partners:
LOC103141530
R-spondin 1.
  
 0.978
rspo2
R-spondin 2.
  
 0.970
ENSPFOP00000025096
R-spondin 4.
  
 0.970
ENSPFOP00000014566
Zinc and ring finger 3.
    
 0.969
RSPO3
R-spondin 3.
  
 0.964
RNF43
Ring finger protein 43.
    
 0.942
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
  
 
 
0.937
LOC103136649
R-spondin 3.
  
 0.937
LGR6
Leucine rich repeat containing G protein-coupled receptor 6.
  
 
 
0.930
ENSPFOP00000017057
Calcium homeostasis endoplasmic reticulum protein.
    
 0.813
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
Server load: low (18%) [HD]