| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPFOP00000001436 | ENSPFOP00000002114 | ENSPFOP00000001436 | ENSPFOP00000002114 | SAS-6 centriolar assembly protein. | Helicase C-terminal domain-containing protein. | 0.967 |
| ENSPFOP00000001436 | ENSPFOP00000011594 | ENSPFOP00000001436 | ENSPFOP00000011594 | SAS-6 centriolar assembly protein. | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | 0.903 |
| ENSPFOP00000001436 | ENSPFOP00000012019 | ENSPFOP00000001436 | ENSPFOP00000012019 | SAS-6 centriolar assembly protein. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.893 |
| ENSPFOP00000001436 | ENSPFOP00000013687 | ENSPFOP00000001436 | ENSPFOP00000013687 | SAS-6 centriolar assembly protein. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.892 |
| ENSPFOP00000001436 | RPA1 | ENSPFOP00000001436 | ENSPFOP00000012296 | SAS-6 centriolar assembly protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.877 |
| ENSPFOP00000001436 | cenpj | ENSPFOP00000001436 | ENSPFOP00000007013 | SAS-6 centriolar assembly protein. | Centromere protein J. | 0.933 |
| ENSPFOP00000001436 | pola2 | ENSPFOP00000001436 | ENSPFOP00000011202 | SAS-6 centriolar assembly protein. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.878 |
| ENSPFOP00000001436 | rad52 | ENSPFOP00000001436 | ENSPFOP00000017436 | SAS-6 centriolar assembly protein. | RAD52 homolog, DNA repair protein. | 0.908 |
| ENSPFOP00000001436 | rpa1 | ENSPFOP00000001436 | ENSPFOP00000004158 | SAS-6 centriolar assembly protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.877 |
| ENSPFOP00000001436 | rpa3 | ENSPFOP00000001436 | ENSPFOP00000008786 | SAS-6 centriolar assembly protein. | Replication protein A3. | 0.927 |
| ENSPFOP00000002114 | ENSPFOP00000001436 | ENSPFOP00000002114 | ENSPFOP00000001436 | Helicase C-terminal domain-containing protein. | SAS-6 centriolar assembly protein. | 0.967 |
| ENSPFOP00000002114 | ENSPFOP00000013687 | ENSPFOP00000002114 | ENSPFOP00000013687 | Helicase C-terminal domain-containing protein. | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. | 0.998 |
| ENSPFOP00000002114 | RPA1 | ENSPFOP00000002114 | ENSPFOP00000012296 | Helicase C-terminal domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.999 |
| ENSPFOP00000002114 | rad52 | ENSPFOP00000002114 | ENSPFOP00000017436 | Helicase C-terminal domain-containing protein. | RAD52 homolog, DNA repair protein. | 0.998 |
| ENSPFOP00000002114 | rpa1 | ENSPFOP00000002114 | ENSPFOP00000004158 | Helicase C-terminal domain-containing protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.999 |
| ENSPFOP00000002114 | rpa3 | ENSPFOP00000002114 | ENSPFOP00000008786 | Helicase C-terminal domain-containing protein. | Replication protein A3. | 0.994 |
| ENSPFOP00000011594 | ENSPFOP00000001436 | ENSPFOP00000011594 | ENSPFOP00000001436 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | SAS-6 centriolar assembly protein. | 0.903 |
| ENSPFOP00000011594 | ENSPFOP00000012019 | ENSPFOP00000011594 | ENSPFOP00000012019 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.999 |
| ENSPFOP00000011594 | RPA1 | ENSPFOP00000011594 | ENSPFOP00000012296 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.839 |
| ENSPFOP00000011594 | pola2 | ENSPFOP00000011594 | ENSPFOP00000011202 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.999 |