Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC103130236NDRG family member 2. (369 aa)    
Predicted Functional Partners:
LOC103139698
Family with sequence similarity 162 member A.
    
 
 0.642
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.539
eef2k
Eukaryotic elongation factor 2 kinase.
      
 0.498
dnajb11
DnaJ heat shock protein family (Hsp40) member B11.
     
 0.473
LOC103147757
Uncharacterized protein.
     
  0.441
ENSPFOP00000000319
Far upstream element (FUSE) binding protein 1.
      
 0.417
cmtr1
Cap methyltransferase 1.
      
 0.417
LOC103131073
Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family.
      
 0.417
TOM1L2
Target of myb1 like 2 membrane trafficking protein.
      
 0.417
p4ha2
Procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide 2.
      
 0.414
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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