Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pias4Protein inhibitor of activated STAT, 4a. (509 aa)    
Predicted Functional Partners:
sumo1
Small ubiquitin like modifier 1.
    
 0.992
rnf168
Ring finger protein 168.
   
 
 0.988
ENSPFOP00000004987
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.986
ube2i
Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.986
ENSPFOP00000002611
Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair.
    
 0.966
brca1
Uncharacterized protein.
    
 0.943
LOC103150116
Small ubiquitin-related modifier.
    
 0.937
sumo2
Small ubiquitin-related modifier.
    
 0.937
LOC103155113
Small ubiquitin-related modifier.
    
 0.937
ENSPFOP00000030884
Small ubiquitin like modifier 3b.
    
 0.937
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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