Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bcl6BCL6A transcription repressor a. (744 aa)    
Predicted Functional Partners:
LOC103149502
Uncharacterized protein.
  
  
 
0.902
ENSPFOP00000018817
Nuclear receptor corepressor 1.
    
 0.854
bcor
BCL6 corepressor.
    
 
 0.847
bcorl1
BCL6 corepressor-like 1.
    
 
 0.847
ENSPFOP00000017719
Nuclear receptor corepressor 2.
    
 0.804
trap1
CREB binding protein b.
    
 0.673
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
   
 0.668
LOC103145125
Uncharacterized protein.
    
 
 0.663
fbxo11
Uncharacterized protein.
    
 
 0.663
cxcr5
Chemokine (C-X-C motif) receptor 5; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.660
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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