Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
LOC103152767Mitogen-activated protein kinase. (364 aa)    
Predicted Functional Partners:
mapkapk2
MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily.
  
0.991
LOC103150707
Mitogen-activated protein kinase kinase 6.
  
 0.985
MAP2K6
Mitogen-activated protein kinase kinase 6.
  
0.983
tp53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.979
ENSPFOP00000010038
Rhodanese domain-containing protein.
    
 0.978
mef2c
Myocyte enhancer factor 2cb.
    
 0.973
mapkapk5
MAPK activated protein kinase 5.
    
0.972
ENSPFOP00000026628
Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family.
    
 0.971
ENSPFOP00000017743
Ribosomal protein S6 kinase.
   
 
0.970
LOC103133881
Ribosomal protein S6 kinase.
   
 
0.970
Your Current Organism:
Poecilia formosa
NCBI taxonomy Id: 48698
Other names: Amazon molly, Limia formosa, Mollienesia formosa, P. formosa
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